Aqueous extract of Agrostemma githago seeds showed the ability to inhibit angiogenesis, which was associated with changes in the release of VEGF, MMP2/9, and ANG2 (angiopoietin-2; crucial in vascular remodelling and tumour angiogenesis) from cancer and endothelial cell lines [93]. This evidence concerns the gene ANGPT2 and neoplasm.