NF-κB also regulates the expression of members of anti-apoptotic proteins, including Bcl-2, Bcl-xL, and A1/Bfl-1, each of which is required for cancer cell survival in metastatic conditions [10], allowing cancer cells to adhere to the extracellular matrix, aiding metastasis and further organismal invasion. This evidence concerns the gene BCL2A1 and cancer.