TMEM43 and Emery-Dreifuss muscular dystrophy: Genetic mutations and gene expression variations in TMEM43 have been associated with many human diseases, including arrhythmogenic cardiomyopathy (ACM), formerly known as arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) [6,7], Emery–Dreifuss Muscular Dystrophy (EDMD) [8,9], and auditory neuropathy spectrum disorders (ANSDs) [10,11], as well as the progression of various cancers in humans [12,13,14].