Notably, lncRNA FTX inhibits ferroptosis in magnesium-free-induced hippocampal neurons via the miR-142-5p/GABPB1 axis [33] and protects against cerebral ischemia–reperfusion injury by enhancing neuronal proliferation and reducing apoptosis through the miR-186-5p/MDM4 pathway [41]. This evidence concerns the gene MDM4 and brain ischemia.