MAPK1 and rheumatoid arthritis: The inhibition of the extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) signaling pathways (ERK/JNK) significantly attenuated the migration and invasion of RA-FLs through leukocyte Ig-like receptor A3 (LILRA3), which resulted in decreased expression of IL-6, IL-8, and MMP3 [232].