These enriched pathways were related to osteoclast differentiation, phagosome, TNF signaling, PI3K-Akt signaling pathways, non-alcoholic fatty liver diseases, T cell leukemia virus-1 infection, Epstein Barr virus infection, NF-kappa B signaling cascade, MAPK signaling pathway, cellular senescence, viral carcinogenesis, and Kaposi sarcoma-associated herpesvirus infection. The gene discussed is TNF; the disease is Epstein-Barr virus infection.