In addition, the pro-inflammatory factor IFN-γ released by CD8+ T cells induces the production of chemokines, including the C-X-C motif chemokine ligands 9 and 10 (CXCL9 and CXCL10), which in turn promote the recruitment of CD8+ T cells to melanocytes and exacerbate the progression of vitiligo [10]. The gene discussed is IFNG; the disease is vitiligo.