TGFB1 and Fuchs endothelial corneal dystrophy: Although, the TCF4 genetic status of our FECD cohort is currently unknown, our RNA seq analysis reveal that TCF4 expression is upregulated following TGF-β1 or TGF-β2 stimulation (Tables S1 and S2), further supporting an association between TCF4 and TGF-β.