PRMT1 and colorectal adenocarcinoma: After the stratification of colorectal adenocarcinoma patients according to their tumor location, we noticed that patients with colon tumors (122 for DFS and 136 for OS) and overexpression of circ-PRMT1 showed significantly shorter DFS intervals (p = 0.026) and OS intervals (p < 0.001) (Figure 5A,B).