For example, circSTK3 upregulates EMT-associated genes; circSKA3 directly binds to and stabilizes snail family transcriptional repressor 2 (SNAI2), a core regulator of EMT; and circEIF3I increases non-SMC condensin I complex subunit H (NCAPH) expression by sequestering miR-328-3p, facilitating CRC progression [14,15,16]. Here, SNAI2 is linked to colorectal carcinoma.