MS4A1 and Huntington disease: More recently, these results were confirmed in a cohort of 17 HD [22], where CD20+ T cells presented a higher proportion of transitional memory cells compared with CD20− T cells and displayed a proinflammatory phenotype characterized by the expansion of T helper (Th)1, Th1/17, and T cytotoxic (Tc)1 cell subsets, associated with a high expression of activation (CD25) and exhaustion (PD-1) markers.