Chaudhary et al. [68] conducted a comprehensive study investigating mRNA expression and secretion levels of MMP-2 and MMP-9 in bone marrow mononuclear cells, as well as genotypic associations of MMP-2 rs243865 and MMP-9 rs3918242 variants in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) during the disease progression. The gene discussed is MMP2; the disease is myelodysplastic syndrome.