NF1 and malignant peripheral nerve sheath tumor: To test the preclinical efficacy of artemisinins as a potential treatment for MPNSTs, we treated a panel of cell lines representing sporadic MPNST (STS26T) and NF1-associated MPNST (S462TY) and utilized normal Schwann cells (iHSC1λ and iHSC2λ) as a control cell line, as they are the cell of origin for MPNST (outlined in Table 1).