Polymorphisms: GSTO1*A140D (C419A; rs4925), GSTO2*N142D (A424G; rs156697), GSTO2 polymorphism in 5′UTR gene region (A183G; rs2297235).Main findings:- shorter survival in male carriers of GSTO1*C/C wild-type genotype (GSTO1*A140) compared to the carriers of at least one variant allele;- increased risk of overall mortality among male ccRCC patients with GSTO1*C/C wild-type genotype. The gene discussed is GSTO2; the disease is nonpapillary renal cell carcinoma.