HPGDS and breast carcinoma: Polymorphisms: GSTO2*N142D (A424G; rs156697) and polymorphisms of other GSTs (GSTM1, GSTT1, GSTP1) Main findings: - increased risk of breast cancer in postmenopausal woman homozygous for GSTO2*N142D; - increased risk of breast cancer in premenopausal women with the combined presence of GSTP1 and GSTO2 polymorphisms.