Having determined that addition of exogenous PL-PUFA alters the lipidome of MM cells (Figure 3A) and can induce ferroptotic cell death (Figure 3B), we hypothesised that altering the lipid composition of MM cells may also sensitise these cells to ferroptosis induced by the GPX4 inhibitor, RSL3. The gene discussed is GPX4; the disease is Miyoshi myopathy.