At first, the top 10 mRNA genes from the MCFS-ID ranking (ADAMTS5, COL10A1, TMEM220, ARHGAP20, MMP11, CAVIN2, PLPP3, MICU3, MME, CD300LG) were screened, and all of them were confirmed to have an association to cancer prediction and development. The gene discussed is CD300LG; the disease is cancer.