However, as seven of these studies had been published before the 2017 WHO classification, all high-grade lesions were considered neuroendocrine carcinomas (NECs), although this likely included some NET G3s; in any case, most of these samples had a score 0 or 1 in IHC (only one sample with a score of 3 and a Ki-67 equal to 30% was reported in the study by Miederer and coworkers) [20]. The gene discussed is MKI67; the disease is neuroendocrine carcinoma.