In particular, increased levels of protein degradation-related markers such as muscle RING Finger 1 (MuRF-1) and F-box only protein 32 (Fbxo32, also known as Muscle Atrophy F-box) contribute to the occurrence of sarcopenia by elevating degradation, leading to muscle atrophy [7]. The gene discussed is FBXO32; the disease is sarcopenia.