Several studies demonstrate the role of the immune-related proteins such as catalase [158], lactoferrin [159], matrix metalloproteinase-9 [160], retinol binding protein 4 [161], and serine protease inhibitor A family member 3 [162] in metabolic pathways and in the regulation of cellular processes, modulation of the host immune system, development, progression, and metastasis in CRC. This evidence concerns the gene RBP4 and colorectal carcinoma.