MMP2 and Bowen disease of the skin: For cases with Bowen’s disease lesions, MMP-2 varied in the range 70–81 RFU/mg protein, with a variance of 18.36%, the median (77.50 RFU/mg protein) was close to the mean level of 76.0 ± 4.29 RFU/mg protein, and the result of the Skewness test (t = −0.291) suggests homogeneity of the series of values (Table 2).