DCAF17 and deafness: Similarly, Woodhouse–Sakati syndrome (caused by biallelic variants in the C2orf37 gene, also known as NBIA/DYT-DCAF17, OMIM#241080) presents with multisystem involvement, including hypogonadism, diabetes, and alopecia along with neurological symptoms such as deafness, dystonia, and IDD [181,183].