PHF20L1 and thyroid gland carcinoma: However, in other cancer types, such as Uterine Corpus Endometrial Carcinoma (UCEC) and thyroid carcinoma (THCA), the expression levels of PHF20L1 were downregulated in tumour tissues compared to those in normal tissues, which suggests that the role of PHF20L1 in these cancers may have an opposite effect (Figure 4B).