Analysis of the Cancer Genome Atlas (TCGA) database using the Gene Expression Profiling Interactive Analysis platform GEPIA 2 (http://gepia2.cancer-pku.cn/, accessed on 25 April 2025) [49] revealed that in some cancer types, such as acute myeloid leukaemia (LAML) and oesophageal adenocarcinoma (ESCA), the expression levels of PHF20L1 in tumour tissues were significantly higher than those in normal tissues. This evidence concerns the gene PHF20L1 and cancer.