DNAJC5 and malaria: The RTS,S subunit vaccine (R = repeat region of the circumsporozoite protein [CSP], T = T-cell epitope of CSP, S = surface antigen of hepatitis B virus [HBsAg], S [extra] = added HBsAg to help form virus-like particles for enhanced immune response), which targets the circumsporozoite protein of Plasmodium falciparum and is formulated with the potent AS01 adjuvant (A = adjuvant system, S01 = specific formulation in the adjuvant system series), is the first malaria vaccine to be approved by the WHO and is currently being rolled out in several African countries [6].