LGALS3 and breast carcinoma: Transfections of the BT-549 human breast carcinoma cell line with serine-to-alanine (S6A) and serine-to-glutamic acid (S6E) mutants of Gal-3 revealed that phosphorylation of Ser172 in the NTD by casein kinase 1 favors Gal-3 export from the nucleus [35,36].