LGALS3 and heart failure: In addition, involvement of Gal-3 has been discovered in the following pathologies and disorders: aortic stenosis, endometriosis, enteric nervous system disorders, encephalitis, fibrosis, gastritis, HIV infection, inflammation, interstitial lung diseases, juvenile idiopathic arthritis, liver fibrosis, non-alcoholic fatty liver disease, obesity, pneumonia, pulmonary hypertension, plaque psoriasis, Q fever, rheumatoid arthritis, sepsis, systematic sclerosis, urinary tract infection, venous thrombosis, and especially heart failure, renal diseases, diabetes mellitus, and various cancers [4,7].