IFNG and type 1 diabetes mellitus: CD4+ T lymphocyte EVs enriched for miR-142-3p, miR-142-5p, and miR-155, upregulate cytokine and chemokine signaling, including Ccl2, Ccl7, IFNγ, and Cxcl10 (T1D associated chemokines), and promote apoptosis in treated β cells [156].