Further genetic analyses have revealed subtype-specific associations of IL-10 single nucleotide polymorphisms (SNPs), where the rs1800896_G allele correlates with increased systemic HIV-NHL risk, while the rs1800871_T and rs1800872_A alleles are associated with a reduced risk of primary central nervous system lymphoma (PCNSL) [51]. The gene discussed is IL10; the disease is non-Hodgkin lymphoma.