PVT1 and nervous system disorder: In fact, several dysregulated lncRNAs that emerged as ASD putative biomarkers have also been observed in the peripheral blood of subjects affected by other neurological disorders; for instance, TUG1 has been proposed as a biomarker for the diagnosis of temporal lobe epilepsy [144], while PVT1 is downregulated in schizophrenia [88], and THRIL is underexpressed in epilepsy [145].