The increased level of TUG1, stabilized by IGF2BP2, promotes the proliferation, migration, and autophagy of CRC cells through the miR-195-5p/HDGF/DDX5/β-catenin pathway, consequently enhancing the resistance of CRC cells to DDP treatment in LS513 and LOVO cell lines [154]. This evidence concerns the gene HDGF and colorectal carcinoma.