As shown in Figure 2 (panel A–D), 46XX cells, at basal condition, showed greater amounts of all myokines analyzed in comparison to 46XY cells, (respectively: for GM-CFS, 14.9 ± 3.2 vs. 1.2 ± 0.2, p = 0.0106 for CXCL1, 4.3 ± 2.5 vs. 3.2 ± 0.2, p = 0.07 (NS); for IL9, 4.2 ± 0.1 vs. 0.8 ± 0.0, ## p = 0.0005; for IL12/p40, 2.7 ± 0.3 vs. 1.3 ± 0.0, ## p = 0.0007;). Here, CXCL1 is linked to myalgic encephalomeyelitis/chronic fatigue syndrome.