Furthermore, the researchers also identified 45 hypermethylated promoters shared by PMOD and oral cancer in known tumor suppressor genes: CDKN1B (cyclin-dependent kinase inhibitor 1B (p27KIP1), ZFP82 (ZFP82 zinc finger protein), SHISA3, (Shisa family member 3), GPX7 (glutathione peroxidase 7), and IRF8 (interferon regulatory factor 8). Here, SHISA3 is linked to neoplasm.