TP53 and neoplasm: 62.5% tumor saliva samples and 18. 5% healthy saliva samples included p53 exon 4 codon 63 mutations (p < 0.05)The main changes of the base substitutions were C-deletionsProbable hot spots for the gene changes were identified at exon 4 codon 63; loss of p53 gene codon 63 (p < 0.05) was noted