To elucidate the role of DIRAS1 in OXA resistance, HCT116 CRC cells were treated with 2 μM OXA and harvested at multiple time points (0, 12, 24, 48, 96, 120, 144, and 168 h) to monitor DIRAS1 expression dynamics. This evidence concerns the gene DIRAS1 and colorectal carcinoma.