This enzyme plays a crucial role in the metabolism of leukotriene B4 (LTB4), a potent inflammatory mediator that has been implicated in the pathogenesis of various cancers due to its ability to promote cell proliferation, angiogenesis, and resistance to apoptosis, CYP4F3 could potentially modulate inflammatory responses and reduce the tumor-promoting effects of chronic inflammation by inactivating LTB4 [59]. The gene discussed is CYP4F3; the disease is cancer.