ESR1 and breast carcinoma: To further analyze CYP4s expression, a correlation was observed between CYP4B1, CYP4F12, CYP4F3, and genes with high incidence in breast cancer, such as the BRCA1 DNA repair-associated (BRCA1), the BRCA2 DNA repair-associated (BRCA2), and the estrogen receptor alpha (ESR1), as seen in Figure 3.