PDE4D and neoplasm: The results showed that dysregulation of the genes PSMD14, STC2, PDE4D, AURKA, LAMC2, CEP55, REALB, ICAM1, STIP1, DTL, TTK, ALG1L, TDO2, ADGRE2, CKAP2, and SERPINE1 had a moderate-to-high effect on distinguishing tumor tissue from healthy tissue, as shown in Figure 4, Figure 5, Figure 6, Figure 7, Figure 8, Figure 9 and Figure 10, Supplementary Figures S1–S12, and Table 4.