A study showed that has-circ-0001445 (circSMARCA5) substantially decreased in the glioma tissue and indirectly regulates the expression of serine/arginine-rich splicing factor 3 (SRSF3) isoforms by interacting with serine and arginine-rich splicing factor 1(SRSF1). This evidence concerns the gene SRSF1 and central nervous system cancer.