Given the impact of PAQR3 knockdown on TSC22D3 (Figure 6A), we also observed that differentially expressed genes were enriched in the Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, and Kaposi sarcoma-associated herpesvirus infection pathways (Figure 5C and Figure S4). The gene discussed is TSC22D3; the disease is Herpesviridae infectious disease.