Additional significant interaction was identified between KRAS and Protein Tyrosine Phosphatase Receptor Type D (PTPRD), RNA-Binding Motif Protein 10 (RBM10), and Neurogenic locus notch homolog protein (NOTCH1/2/3), reflecting novel immune-related mechanisms in KRAS-mutant lung adenocarcinomas. The gene discussed is PTPRD; the disease is lung adenocarcinoma.