To validate the in vitro findings in a clinical setting, we analyzed the protein expression of ERRα, PGC-1α, HIF-1α, and P-gp in a TMA containing 144 invasive carcinoma cases and 24 invasive lobular carcinoma cases (Figure 6, Supplementary Table S1). The gene discussed is HIF1A; the disease is invasive lobular breast carcinoma.