TRIM59 and neoplasm: TRIM family proteins, which act as tumor promoters, include TRIM24 [28,35], TRIM27 [24,26,28], TRIM37 [41], TRIM44 [42], TRIM46 [43], TRIM47 [44], TRIM58 [26,45], TRIM59 [46], TRIM63 [47], and TRIM65 [26,48].