A total of 27 TRIM family proteins were cancer-associated, of which 9 were associated with oncogenic findings (TRIM24, TRIM27, TRIM37, TRIM44, TRIM46, TRIM47, TRIM59, TRIM63, and TRIM65) and 9 TRIM family proteins (TRIM2, TRIM7, TRIM8, TRIM13, TRIM21, TRIM26, TRIM28, TRIM33, and TRIM58) were associated with tumor-suppressive evidence (Table 1) [23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48]. The gene discussed is TRIM8; the disease is neoplasm.