Since our previous research based on scRNA-seq data demonstrated the predominant expression of MICA in HCC tumor cells [15], the co-expression of MICA and EHHADH in HCC (Figure 1c), and the confirmation of the significant correlation between MICA and EHHADH expression with macrophage infiltration in HCC (Figures S3–S5 and Figure 2), as well as the negative correlation between EHHADH and MICA (Figures S4a and S5g and Figure 2h), we proceeded to investigate the cell clusters in which EHHADH was expressed. Here, EHHADH is linked to hepatocellular carcinoma.