In contrast, CD34+ cell dose was not associated with the development of grade 2–4 acute GVHD (continuous variable: HR [per 1.0 × 106/kg increase in CD34+ cell dose] = 1.02 [0.98–1.05], p = 0.33; low vs. high CD34+ group: HR = 0.96 [0.71–1.31], p = 0.81) or grade 3–4 acute GVHD (continuous variable: HR =1.00 [0.91–1.10], p = 0.99; low vs. high CD34+ group: HR = 1.57 [0.83–2.98], p = 0.17). This evidence concerns the gene CD34 and acute graft versus host disease.