First, prolonged consumption of desserts, including cookies, may be nutritionally detrimental for carbohydrate (insulin resistance, high glycemic response, etc.)or lipid metabolism (changes to the serum lipid profile, obesity, etc.); the consumption of foods rich in phenolics could therefore be performed in a matrix that contains a lower sugar and fat content. Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.