In contrast, the overexpression of Nrf2 and HO-1 in NSCLC cell lines, such as NCI-H292, SK-MES-1, and NCI-H460, promotes the expression of thymidine phosphorylase, IL-6, and IL-1β and subsequently facilitates tumor-associated angiogenesis [57]. The gene discussed is HMOX1; the disease is neoplasm.