In humans, divicine triggers ROS generation in erythrocytes, depleting glutathione (GSH) and nicotinamide adenine dinucleotide phosphate (NADPH) to induce favism in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency [18,19]. This evidence concerns the gene G6PD and hyperinsulinemic hypoglycemia, familial, 4.