TRPM2 Inhibition (chemical/genetic: SiRNA/KO):Breast cancer cells↓Proliferation ↑DNA damage [178].Neuroblastoma cells ↓Viability↑ROS ↑DNA damage (sensitised to doxorubicin) [179].Leukaemia ↓Proliferation ↑Chemo sensitivity [180].Ovarian Cancer ↓Cell viability ↓Proliferation↑Apoptosis [181].PC3 and HeLa↓Cell migration [115]. This evidence concerns the gene TRPM2 and ovarian carcinoma.