Ang II stimulates vascular endothelial growth factor A (VEGF-A) expression through the epidermal growth factor receptor (EGFR), mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase (ERK1/2), and PI3K/AKT pathways, facilitating neovascularization in various cancers [97]. Here, AKT1 is linked to cancer.