The GR agonist dexamethasone induced a gene signature that correlated with shorter survival in The Cancer Genome Atlas glioblastoma dataset [72], enhanced tumor growth and metastasis in breast cancer xenograft mouse models [73], transcriptionally activated TEA domain transcription factor 4, the expression of which correlates with poor survival of patients with breast cancer [74], and favored epithelial–mesenchymal transition, self-renewal potential, and cancer progression in pancreatic ductal adenocarcinoma cell lines [75]. This evidence concerns the gene NR3C1 and breast cancer.