BEST1 and autosomal recessive bestrophinopathy: Pathogenic variants in BEST1 can lead to a spectrum of bestrophinopathies, including best vitelliform macular dystrophy (BVMD, OMIM # 153700) [11], adult-onset vitelliform macular degeneration (AVMD, OMIM # 179605) [12], autosomal dominant vitreoretinochoroidopathy (ADVIRC, OMIM # 193220) [13], autosomal recessive bestrophinopathy (ARB, OMIM # 611809) [14], and retinitis pigmentosa (RP, OMIM # 613194) [15].