GLP-1 has emerged as a prominent therapeutic target for type 2 diabetes mellitus (T2DM) and obesity and has recently been shown to have potential therapeutic effects on comorbidities in these populations, such as autoimmune processes, chronic kidney disease (CKD), cardiovascular disease, and Alzheimer’s disease [10]. This evidence concerns the gene GLP1R and obesity due to melanocortin 4 receptor deficiency.