GPT and Wilson disease: Similarly, serum biochemistry showed an increase in alanine transaminase (p ≤ 0.05), aspartate transaminase (p ≤ 0.001), alkaline phosphatase (p ≤ 0.001), gamma glutamyl transferase (p ≤ 0.05), and lactate dehydrogenase (p ≤ 0.01) in WD compared with SD (Table 3).