We also demonstrated that four biomarkers were significantly elevated in patients with AAA (HE4/WFDC2, MMP-3, BAFF/BlyS, and Cathepsin S), and three were linearly associated with AAA diameter at baseline (HE4/WFDC2, MMP-3, Chitinase-3 like 1). Here, CHI3L1 is linked to triple-A syndrome.