Likewise, high concentrations prior to the diagnosis of inflammation markers such as C-reactive protein have been reported, and several cytokines such as IL-1, IL-6, IL-8, TNF-α, among others, have been associated with a high risk of developing some types of cancer including breast, lung, prostate, ovarian and colorectal cancer [37,38]. The gene discussed is IL1B; the disease is colorectal cancer.